Depression has been linked recently in article and studies to inflammation. A recent study Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study. looked at the effects of curcumin (500 mg twice daily) or placebo for 8 weeks on individuals with major depressive disorder. There was some positive results in favour of curcumin, enough to warrant further investigation. Another study Curcumin and major depression: a randomised, double-blind, placebo-controlled trial investigating the potential of peripheral biomarkers to predict treatment response and antidepressant mechanisms of change looked at the same dosage of curcumin and found ‘ that curcumin supplementation influences several biomarkers that may be associated with its antidepressant mechanisms of action.’ Could curcumin in conjunction with an anti-inflammatory diet produce a better effect? Dr Weil thinks that is a convincing idea. It is also intersting to me that St. John’s Wort which has shown some effect on mild depression but is vastly over marketed for it, has always been thought of as a nerve anti-inflammatory, healing to heal nerve injury and reduce pain. Jim McDonald talks about it in treatment of back pain and nerves…
Spring seems to have arrived after a shaky start! The last 2 posts on seasonal allergies covered supplements, herbs, probiotics, and nutraceuticals.
In addition to trying supplements either herbal or nutraceutical you could also try nasal irrigation for your allergies. Several studies have shown that nasal irrigation can reduce the symptoms of seasonal rhinitis.
Echinacea is an amazing herb and after being touted as THE herb for the common cold was found on every health food store and pharmacy shelf. The problem is the quality of these products is widely variable and the recommended dosages are broad, some of them being ineffectual. The Cochrane Review Echinacea for preventing and treating the common cold says,
Most consumers and physicians are not aware that products available under the term Echinacea differ appreciably in their composition, mainly due to the use of variable plant material, extraction methods and the addition of other components.
- Use Echinacea purpurea alone or in combination with Echiniacea augustifolia
- Liquid may be preferable as there is come evidence that actual contact with the oral mucosa is more effective
- Francis Brinker noted that Echinacea trials that used liquid extracts showed positive outcomes in upper respiratory infections
- Start the dosing regime at the very -first- signs of sickness
- Use a loading dose of 5 mL (capsule 1500 mg), followed by 2.5 mL (500-750 mg) every 1-2 hours for the first day
- The liquid dose is based on a 1:2 fresh root extract
- For the next 2 days use 5 mL (1500mg) three times a day
- For children use Clark’s rule to calculate the dose